ZBTB41

Across TCGA pan-cancer cohorts, ZBTB41 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated ZBTB41 data layer compared with 24 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher ZBTB41 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated ZBTB41 expression acts as an unfavorable survival marker, although some lineages such as LSCC show a favorable association.

PDAC, LUAD, and LSCC are the cancer types where ZBTB41 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Median	III,IV	0.603	0.880	.024	11	view →
LUAD	DFS	Quartile	All	0.567	1.000	.023	6	view →
LSCC	OS	Median	All	1.000	0.948	.046	2	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

ZBTB41–PDAC (DFS)

Open the PDAC breakdown →