ZBTB41

Across TCGA cell cohorts, ZBTB41 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,820 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZBTB41-associated GO terms across cancer lineages are Negative regulation of hematopoietic stem cell differentiation, Establishment of protein localization to vacuole, and Protein modification by small protein removal. Each is linked with ZBTB41 in more than 13 cancer types. Because this analysis shows association rather than direction, both ZBTB41-to-partner and partner-to-ZBTB41 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of hematopoietic stem cell differentiation grouped by ZBTB41-low versus ZBTB41-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB41→partner) and Y-score (partner→ZBTB41) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Negative regulation of hematopoietic stem cell differentiation →	+0.132	+0.743	<.001	<.001	3	14
BONE	Establishment of protein localization to vacuole →	+0.062	+0.601	<.001	<.001	3	13
OESOPHAGUS	Protein modification by small protein removal →	+0.066	+0.759	.002	.002	3	13
OVARY	Vesicle tethering →	+0.062	+0.718	.002	<.001	3	13
OESOPHAGUS	Macroautophagy →	+0.048	+0.481	.004	.002	3	12
BONE	Golgi organization →	+0.056	+0.610	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,820 associations by consensus.

Negative regulation of hematopoietic stem cell differentiation by ZBTB41 expression — PANCREAS

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