ZBTB41

Across TCGA cell cohorts, ZBTB41 mutation is significantly associated with the mutation status of many other genes, with 4,744 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZBTB41-associated genes across cancer lineages are ANK1, TLE1, and SMCHD1. Each is linked with ZBTB41 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZBTB41-to-partner and partner-to-ZBTB41 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ANK1 grouped by ZBTB41-low versus ZBTB41-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB41→partner) and Y-score (partner→ZBTB41) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ANK1 →	+1.989	+2.148	.003	.003	1	5
BLOOD_Lymphoma	TLE1 →	+4.014	+4.969	.008	.008	1	4
UPPER_AERODIGESTIVE_TRACT	SMCHD1 →	+5.392	+5.392	.004	.004	1	4
UPPER_AERODIGESTIVE_TRACT	EIF4G2 →	+5.392	+5.392	.004	.004	1	4
BLOOD_Lymphoma	EPHB2 →	+4.429	+5.247	.005	.005	1	4
BLOOD_Lymphoma	PRPF38B →	+5.014	+5.584	.003	.003	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,744 associations by consensus.

ANK1 by ZBTB41 expression — LARGE_INTESTINE

Explore this box plot interactively →