Across TCGA patient cohorts, ZBTB40 protein abundance is significantly associated with the RNA expression of many other genes, with 5,782 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZBTB40-associated genes across cancer lineages are RPL22, IQCC, and EXOSC10. Each is linked with ZBTB40 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZBTB40-to-partner and partner-to-ZBTB40 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB40→partner) and Y-score (partner→ZBTB40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RPL22 →	+0.475	+0.238	<.001	<.001	3	3
BRCA	IQCC →	+0.525	+0.320	<.001	<.001	3	3
BRCA	EXOSC10 →	+0.285	+0.224	.003	<.001	3	3
LSCC	SLC2A4 →	+0.617	+0.219	<.001	.001	3	3
LSCC	AIFM3 →	-0.401	-0.160	.001	<.001	3	3
BRCA	HMGN2P5 →	+0.604	+0.243	.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,782 associations by consensus.

Exploration

ZBTB40 survival (RNA) · tumor vs normal (RNA) · all ZBTB40 data types