Across TCGA patient cohorts, ZBTB40 mutation is significantly associated with the total protein of many other genes, with 46 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZBTB40-associated genes across cancer lineages are GAPDH, HER3_pY1289, and Bad_pS112. Each is linked with ZBTB40 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZBTB40-to-partner and partner-to-ZBTB40 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB40→partner) and Y-score (partner→ZBTB40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GAPDH →	+0.417	+1.584	.007	.008	3	3
UCEC	HER3_pY1289 →	+0.053	+0.970	.036	.041	3	3
SKCM	Bad_pS112 →	+0.184	+2.472	.022	.010	3	2
UCEC	eIF4E →	+0.172	+2.920	.004	<.001	3	2
UCEC	GATA6 →	-0.129	-1.985	.004	.008	3	2
UCEC	INPP4B →	-0.291	-2.201	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 46 associations by consensus.

Exploration

ZBTB40 survival (RNA) · tumor vs normal (RNA) · all ZBTB40 data types