Across TCGA cell cohorts, ZBTB40 mutation is significantly associated with the RNA expression of many other genes, with 40 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZBTB40-associated genes across cancer lineages are OR1E3, KCNK18, and SLC22A24. Each is linked with ZBTB40 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZBTB40-to-partner and partner-to-ZBTB40 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB40→partner) and Y-score (partner→ZBTB40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	OR1E3 →	+0.036	+4.906	<.001	.006	3	1
OESOPHAGUS	KCNK18 →	+0.020	+4.906	<.001	.006	3	1
OESOPHAGUS	SLC22A24 →	+0.006	+4.906	<.001	.006	3	1
OESOPHAGUS	LCE1F →	+0.330	+4.906	<.001	.006	3	1
CNS	GP9 →	+0.032	+5.754	<.001	.002	3	1
LUNG_SCLC	PRAMEF10 →	+1.180	+5.643	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 40 associations by consensus.

Exploration

ZBTB40 survival (RNA) · tumor vs normal (RNA) · all ZBTB40 data types