ZBTB4

Across TCGA patient cohorts, ZBTB4 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,205 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ZBTB4-associated proteins across cancer lineages are DDX21_S89, RPL5, and PAFAH1B1. Each is linked with ZBTB4 in more than 6 cancer types. Because this analysis shows association rather than direction, both ZBTB4-to-partner and partner-to-ZBTB4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZBTB4 versus DDX21_S89 in BRCA, with a Pearson correlation of -0.58.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB4→partner) and Y-score (partner→ZBTB4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	DDX21_S89 →	-1.194	-0.764	<.001	<.001	3	7
BRCA	RPL5 →	-0.251	-0.632	<.001	<.001	3	7
GBM	PAFAH1B1 →	+0.270	+0.458	<.001	<.001	3	7
BRCA	RPL6 →	-0.386	-0.415	<.001	.002	3	6
BRCA	DDX21_S71 →	-1.306	-0.662	<.001	<.001	3	6
UCEC	LMNA →	+0.445	+0.377	.002	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,205 associations by consensus.

ZBTB4 vs DDX21_S89 — BRCA

Explore this scatter interactively →