ZBTB38

Across TCGA patient cohorts, ZBTB38 mutation is significantly associated with the RNA expression of many other genes, with 4,632 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZBTB38-associated genes across cancer lineages are AGGF1P4, MIR4769, and ARFGAP3. Each is linked with ZBTB38 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZBTB38-to-partner and partner-to-ZBTB38 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AGGF1P4 grouped by ZBTB38-low versus ZBTB38-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB38→partner) and Y-score (partner→ZBTB38) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	AGGF1P4 →	+0.087	+7.503	<.001	<.001	3	3
CESC	MIR4769 →	+0.334	+5.164	<.001	.002	3	3
UCEC	ARFGAP3 →	+0.462	+2.065	.001	.001	3	3
LGG	RN7SL299P →	+0.314	+5.936	<.001	.002	3	3
LGG	MIR8053 →	+0.577	+6.787	<.001	<.001	3	3
LIHC	LINC00349 →	+0.091	+5.014	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,632 associations by consensus.

AGGF1P4 by ZBTB38 expression — LIHC

Explore this box plot interactively →