Across TCGA patient cohorts, ZBTB37 mutation is significantly associated with the total protein of many other genes, with 18 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZBTB37-associated genes across cancer lineages are EGFR_pY1068, ERK2, and ACC1. Each is linked with ZBTB37 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZBTB37-to-partner and partner-to-ZBTB37 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB37→partner) and Y-score (partner→ZBTB37) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.325	-2.169	<.001	.003	3	1
UCEC	ERK2 →	+0.147	+1.415	.041	.046	3	1
UCEC	ACC1 →	+0.302	+3.335	.026	.005	3	1
UCEC	Acetyl-a-Tubulin-Lys40 →	+0.529	+1.765	.005	.014	3	1
UCEC	JNK_pT183_Y185 →	-0.187	-3.700	.003	.001	3	1
UCEC	MAPK_pT202_Y204 →	-0.394	-2.115	.025	.017	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

Exploration

ZBTB37 survival (RNA) · tumor vs normal (RNA) · all ZBTB37 data types