ZBTB33

Across TCGA patient cohorts, ZBTB33 mutation is significantly associated with the RNA expression of many other genes, with 6,960 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZBTB33-associated genes across cancer lineages are ATP5PFP1, EMC9, and EIF2B2. Each is linked with ZBTB33 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZBTB33-to-partner and partner-to-ZBTB33 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATP5PFP1 grouped by ZBTB33-low versus ZBTB33-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB33→partner) and Y-score (partner→ZBTB33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ATP5PFP1 →	+0.147	+2.839	.001	.004	3	3
UCEC	EMC9 →	+0.322	+1.219	<.001	.001	3	3
UCEC	EIF2B2 →	+0.346	+1.354	<.001	<.001	3	3
UCEC	GOT1 →	+0.336	+1.938	<.001	<.001	3	3
UCEC	ATP1B2 →	-0.625	-2.474	<.001	<.001	3	3
UCEC	H2AZ1 →	+0.746	+3.091	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,960 associations by consensus.

ATP5PFP1 by ZBTB33 expression — LUAD

Explore this box plot interactively →