ZBTB33

Across TCGA cell cohorts, ZBTB33 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,157 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZBTB33-associated GO terms across cancer lineages are mRNA 3'-end processing, Sex-chromosome dosage compensation, and scaRNA localization to Cajal body. Each is linked with ZBTB33 in more than 15 cancer types. Because this analysis shows association rather than direction, both ZBTB33-to-partner and partner-to-ZBTB33 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mRNA 3'-end processing grouped by ZBTB33-low versus ZBTB33-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB33→partner) and Y-score (partner→ZBTB33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	mRNA 3'-end processing →	+0.104	+0.698	<.001	<.001	3	16
BLOOD_Lymphoma	Sex-chromosome dosage compensation →	+0.100	+1.126	.001	<.001	3	14
BONE	scaRNA localization to Cajal body →	+0.097	+0.665	.005	.004	3	14
PANCREAS	Positive regulation of telomerase RNA localization to Cajal body →	+0.109	+0.794	<.001	<.001	3	14
SOFT_TISSUE	Negative regulation of protein ubiquitination →	+0.079	+0.686	<.001	<.001	3	13
LUNG_SCLC	Random inactivation of X chromosome →	+0.116	+0.914	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,157 associations by consensus.

mRNA 3'-end processing by ZBTB33 expression — BONE

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