ZBTB33

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ZBTB33 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZBTB33-associated genes across cancer lineages are TAAR6, OR2V1, and DPYS. Each is linked with ZBTB33 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZBTB33-to-partner and partner-to-ZBTB33 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TAAR6 grouped by ZBTB33-low versus ZBTB33-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB33→partner) and Y-score (partner→ZBTB33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STOMACHTAAR6 →+0.021+4.794<.001.00131
STOMACHOR2V1 →+0.064+4.129.005.00731
LARGE_INTESTINEDPYS →+0.084+3.813.001.00331
LARGE_INTESTINEITGAD →+0.013+4.832<.001<.00131
LARGE_INTESTINEBPIFB6 →+0.016+4.022<.001.00631
LARGE_INTESTINEIFIT1B →+0.044+4.145<.001.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

TAAR6 by ZBTB33 expression — STOMACH

Box plot of TAAR6 in ZBTB33-low vs ZBTB33-high samples in STOMACH.

Explore this box plot interactively →

Exploration