ZBTB32

Across TCGA cell cohorts, ZBTB32 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZBTB32-associated genes across cancer lineages are MRAP, TSPY3, and C1orf232. Each is linked with ZBTB32 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZBTB32-to-partner and partner-to-ZBTB32 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MRAP grouped by ZBTB32-low versus ZBTB32-high in UPPER_AERODIGESTIVE_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB32→partner) and Y-score (partner→ZBTB32) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	MRAP →	+0.028	+4.736	<.001	.009	3	1
UPPER_AERODIGESTIVE_TRACT	TSPY3 →	+0.626	+4.736	<.001	.009	3	1
UPPER_AERODIGESTIVE_TRACT	C1orf232 →	+0.084	+4.736	<.001	.009	3	1
LARGE_INTESTINE	TLX3 →	+0.401	+2.845	.002	.009	3	1
LARGE_INTESTINE	ARL13A →	+0.082	+3.632	<.001	.003	3	1
LARGE_INTESTINE	FAM205A →	+0.025	+3.614	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

MRAP by ZBTB32 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →