ZBTB25

Across TCGA patient cohorts, ZBTB25 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,289 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZBTB25-associated proteins across cancer lineages are MTA1, SSRP1, and MTHFD1. Each is linked with ZBTB25 in more than 6 cancer types. Because this analysis shows association rather than direction, both ZBTB25-to-partner and partner-to-ZBTB25 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZBTB25 versus MTA1 in LSCC, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB25→partner) and Y-score (partner→ZBTB25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MTA1 →	+0.381	+0.316	.002	.004	3	7
LSCC	SSRP1 →	+0.563	+0.489	<.001	<.001	3	7
BRCA	MTHFD1 →	+0.302	+0.445	<.001	<.001	3	6
BRCA	NEK9 →	+0.269	+0.392	<.001	<.001	3	6
GBM	UBR7 →	+0.376	+0.312	<.001	.001	3	6
GBM	APEX1 →	+0.442	+0.474	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,289 associations by consensus.

ZBTB25 vs MTA1 — LSCC

Explore this scatter interactively →