ZBTB25

Across TCGA cell cohorts, ZBTB25 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,024 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZBTB25-associated GO terms across cancer lineages are Positive regulation of lymphoid progenitor cell differentiation, Cilium-dependent cell motility, and Cilium or flagellum-dependent cell motility. Each is linked with ZBTB25 in more than 17 cancer types. Because this analysis shows association rather than direction, both ZBTB25-to-partner and partner-to-ZBTB25 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of lymphoid progenitor cell differentiation grouped by ZBTB25-low versus ZBTB25-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB25→partner) and Y-score (partner→ZBTB25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Positive regulation of lymphoid progenitor cell differentiation →	+0.142	+0.805	<.001	<.001	3	18
LARGE_INTESTINE	Cilium-dependent cell motility →	-0.069	-0.419	.001	.005	3	14
LARGE_INTESTINE	Cilium or flagellum-dependent cell motility →	-0.069	-0.419	.001	.005	3	14
LUNG_NSCLC_LUAD	Sperm motility →	-0.075	-0.673	.001	<.001	3	13
BONE	Cilium movement involved in cell motility →	-0.084	-0.592	<.001	.001	3	13
LUNG_NSCLC_LUAD	Flagellated sperm motility →	-0.075	-0.673	.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,024 associations by consensus.

Positive regulation of lymphoid progenitor cell differentiation by ZBTB25 expression — LUNG_SCLC

Explore this box plot interactively →