ZBTB24

Across TCGA patient cohorts, ZBTB24 mutation is significantly associated with the total protein of many other genes, with 29 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZBTB24-associated genes across cancer lineages are FASN, AMPK_pT172, and Tuberin. Each is linked with ZBTB24 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZBTB24-to-partner and partner-to-ZBTB24 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FASN grouped by ZBTB24-low versus ZBTB24-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB24→partner) and Y-score (partner→ZBTB24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FASN →	+0.330	+1.584	.033	.036	3	3
UCEC	AMPK_pT172 →	+0.329	+2.459	.041	.019	3	2
UCEC	Tuberin →	+0.325	+2.000	.002	.010	3	2
UCEC	CD49b →	-0.251	-2.302	.024	.034	3	2
COAD	Caspase-7-cleavedD198 →	+1.410	+2.815	.001	.036	3	2
UCEC	EGFR_pY1068 →	-0.304	-2.000	.002	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

FASN by ZBTB24 expression — UCEC

Explore this box plot interactively →