ZBTB24

Across TCGA cell cohorts, ZBTB24 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,429 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZBTB24-associated GO terms across cancer lineages are Regulation of termination of RNA polymerase II transcription, Regulation of termination of DNA-templated transcription, and Negative regulation of RNA export from nucleus. Each is linked with ZBTB24 in more than 15 cancer types. Because this analysis shows association rather than direction, both ZBTB24-to-partner and partner-to-ZBTB24 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of termination of RNA polymerase II transcription grouped by ZBTB24-low versus ZBTB24-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB24→partner) and Y-score (partner→ZBTB24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of termination of RNA polymerase II transcription →	+0.159	+0.588	.001	.001	3	16
OESOPHAGUS	Regulation of termination of DNA-templated transcription →	+0.159	+0.588	.001	.001	3	16
PANCREAS	Negative regulation of RNA export from nucleus →	+0.124	+0.553	<.001	.002	3	16
BONE	DNA-templated DNA replication →	+0.136	+0.720	.001	<.001	3	16
BONE	Protein import into nucleus →	+0.069	+0.573	.003	.004	3	16
LUNG_NSCLC_LUSC	7-methylguanosine mRNA capping →	+0.124	+0.692	.002	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,429 associations by consensus.

Regulation of termination of RNA polymerase II transcription by ZBTB24 expression — OESOPHAGUS

Explore this box plot interactively →