ZBTB24

Across TCGA cell cohorts, ZBTB24 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ZBTB24-associated genes across cancer lineages are GABRA6, MAGEB4, and OR10W1. Each is linked with ZBTB24 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZBTB24-to-partner and partner-to-ZBTB24 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GABRA6 grouped by ZBTB24-low versus ZBTB24-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB24→partner) and Y-score (partner→ZBTB24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	GABRA6 →	+0.051	+4.189	<.001	.002	3	1
LARGE_INTESTINE	MAGEB4 →	+0.012	+5.415	.009	.004	3	1
LARGE_INTESTINE	OR10W1 →	+0.022	+4.977	<.001	.007	3	1
SKIN	BTNL3 →	+0.023	+4.054	<.001	.004	3	1
SKIN	TBC1D28 →	+0.043	+3.920	<.001	.005	3	1
SKIN	OR51A4 →	+0.008	+4.437	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

GABRA6 by ZBTB24 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →