ZBTB21

Across TCGA patient cohorts, ZBTB21 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,976 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZBTB21-associated proteins across cancer lineages are ZBTB21_S714, ZBTB21_S345, and ZFP36L1_S54. Each is linked with ZBTB21 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZBTB21-to-partner and partner-to-ZBTB21 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZBTB21 versus ZBTB21_S714 in LSCC, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB21→partner) and Y-score (partner→ZBTB21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ZBTB21_S714 →	+0.477	+0.495	<.001	<.001	3	5
LUAD	ZBTB21_S345 →	+0.305	+0.386	.001	<.001	3	4
BRCA	ZFP36L1_S54 →	+0.412	+0.514	<.001	.002	3	4
LUAD	ZBTB21_T1005 →	+0.636	+0.575	<.001	<.001	3	4
CCRCC	BCL2L13_S371 →	-0.535	-0.358	.001	<.001	3	3
COAD	BRD3 →	+0.269	+0.494	.008	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,976 associations by consensus.

ZBTB21 vs ZBTB21_S714 — LSCC

Explore this scatter interactively →