ZBTB21

Across TCGA cell cohorts, ZBTB21 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,514 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZBTB21-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Protein polyubiquitination, and Golgi vesicle transport. Each is linked with ZBTB21 in more than 12 cancer types. Because this analysis shows association rather than direction, both ZBTB21-to-partner and partner-to-ZBTB21 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by ZBTB21-low versus ZBTB21-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB21→partner) and Y-score (partner→ZBTB21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Negative regulation of myoblast fusion →	+0.112	+0.693	<.001	.005	3	13
UPPER_AERODIGESTIVE_TRACT	Protein polyubiquitination →	+0.058	+0.765	<.001	.001	3	13
UPPER_AERODIGESTIVE_TRACT	Golgi vesicle transport →	+0.076	+0.886	<.001	<.001	3	13
SKIN	Phosphatidylinositol biosynthetic process →	+0.047	+0.510	<.001	.001	3	13
STOMACH	Regulation of macroautophagy →	+0.077	+0.912	.002	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Cytosolic transport →	+0.076	+0.651	.001	.003	2	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,514 associations by consensus.

Negative regulation of myoblast fusion by ZBTB21 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →