ZBTB20

Across TCGA patient cohorts, ZBTB20 protein abundance is significantly associated with the RNA expression of many other genes, with 16,342 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZBTB20-associated genes across cancer lineages are ADAMTS9-AS2, PLSCR4, and HMGA1. Each is linked with ZBTB20 in more than 7 cancer types. Because this analysis shows association rather than direction, both ZBTB20-to-partner and partner-to-ZBTB20 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZBTB20 versus ADAMTS9-AS2 in UCEC, with a Pearson correlation of 0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB20→partner) and Y-score (partner→ZBTB20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ADAMTS9-AS2 →	+1.184	+0.372	<.001	<.001	3	8
BRCA	PLSCR4 →	+1.324	+0.478	<.001	<.001	3	7
LSCC	HMGA1 →	-1.002	-0.294	<.001	.001	3	7
PDAC	CEP55 →	-0.891	-0.350	<.001	<.001	3	7
BRCA	MFAP4 →	+1.767	+0.393	<.001	.004	3	7
CCRCC	CSDC2 →	+1.193	+0.256	.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,342 associations by consensus.

ZBTB20 vs ADAMTS9-AS2 — UCEC

Explore this scatter interactively →