ZBTB20

Across TCGA patient cohorts, ZBTB20 mutation is significantly associated with the RNA expression of many other genes, with 5,398 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZBTB20-associated genes across cancer lineages are OIP5, ACBD5, and PDS5A. Each is linked with ZBTB20 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZBTB20-to-partner and partner-to-ZBTB20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OIP5 grouped by ZBTB20-low versus ZBTB20-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB20→partner) and Y-score (partner→ZBTB20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	OIP5 →	+0.871	+2.879	<.001	<.001	3	4
STAD	ACBD5 →	+0.776	+3.597	<.001	.001	3	4
LUAD	PDS5A →	+0.615	+3.471	<.001	.002	3	4
UCEC	CCNF →	+0.577	+2.400	<.001	<.001	3	4
UCEC	LEO1 →	+0.550	+2.180	<.001	<.001	3	4
UCEC	SCFD1 →	+0.402	+2.436	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,398 associations by consensus.

OIP5 by ZBTB20 expression — UCEC

Explore this box plot interactively →