ZBTB20

Across TCGA cell cohorts, ZBTB20 mutation is significantly associated with the RNA expression of many other genes, with 779 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZBTB20-associated genes across cancer lineages are BBS7, CNOT6L, and LYG1. Each is linked with ZBTB20 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZBTB20-to-partner and partner-to-ZBTB20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BBS7 grouped by ZBTB20-low versus ZBTB20-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB20→partner) and Y-score (partner→ZBTB20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	BBS7 →	+0.613	+2.523	.001	.003	3	3
LARGE_INTESTINE	CNOT6L →	+0.804	+3.321	<.001	.003	3	3
LARGE_INTESTINE	LYG1 →	+0.971	+2.628	<.001	.002	3	3
LARGE_INTESTINE	SPATA5L1 →	+0.409	+2.628	.004	.002	3	3
LARGE_INTESTINE	RFX7 →	+0.680	+3.321	.001	.003	3	3
LARGE_INTESTINE	ZNF101 →	+0.466	+3.321	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 779 associations by consensus.

BBS7 by ZBTB20 expression — LARGE_INTESTINE

Explore this box plot interactively →