ZBTB20-AS3

Across TCGA pan-cancer cohorts, ZBTB20-AS3 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated ZBTB20-AS3 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher ZBTB20-AS3 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ZBTB20-AS3 expression acts as an unfavorable survival marker, although some lineages such as LGG and SKCM show a favorable association.

KIRC, KIRP, and CHOL are the cancer types where ZBTB20-AS3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	II,III,IV	0.353	0.597	<.001	96	view →
KIRP	OS	Tertile	III,IV	0.107	0.539	.006	75	view →
CHOL	DFS	Tertile	II,III,IV	0.016	0.406	<.001	72	view →
LUSC	OS	Tertile	III,IV	0.140	0.749	.001	60	view →
LGG	OS	Tertile	All	0.945	0.874	.008	19	view →
UCEC	OS	Tertile	IV	0.308	0.748	.009	18	view →
SKCM	OS	Tertile	III,IV	0.772	0.360	.004	15	view →
LAML	DFS	Median	All	0.690	0.441	.016	12	view →
PRAD	DFS	Tertile	All	0.933	0.861	.013	8	view →
CESC	OS	Tertile	All	0.971	0.859	.036	6	view →
BLCA	OS	Tertile	III,IV	0.697	0.517	.042	3	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

ZBTB20-AS3–KIRC (OS)

Open the KIRC breakdown →