ZBTB20-AS1

Across TCGA pan-cancer cohorts, ZBTB20-AS1 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated ZBTB20-AS1 data layer.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher ZBTB20-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated ZBTB20-AS1 expression acts as an unfavorable survival marker, although some lineages such as SKCM and HNSC show a favorable association.

SKCM, HNSC, and CESC are the cancer types where ZBTB20-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	OS	Median	All	0.424	0.244	<.001	100	view →
HNSC	DFS	Tertile	II,III,IV	0.694	0.526	<.001	98	view →
CESC	OS	Median	All	0.880	0.717	<.001	54	view →
BLCA	OS	Quartile	III,IV	0.787	0.467	.011	43	view →
BRCA	OS	Quartile	II,III,IV	0.602	0.477	.003	34	view →
THYM	OS	Quartile	II,III,IV	0.682	1.000	.007	30	view →
KIRC	OS	Median	All	0.768	0.839	.010	26	view →
READ	DFS	Quartile	All	0.459	0.917	.006	26	view →
ACC	DFS	Tertile	IV	0.113	0.550	.005	18	view →
UCS	DFS	Tertile	IV	0.857	0.321	.024	16	view →
LUAD	DFS	Median	III,IV	0.373	0.618	.016	14	view →
OV	OS	Tertile	IV	0.200	0.449	.006	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

ZBTB20-AS1–SKCM (OS)

Open the SKCM breakdown →