ZBTB17

Across TCGA cell cohorts, ZBTB17 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,710 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZBTB17-associated GO terms across cancer lineages are Regulation of translational initiation, RISC complex assembly, and Regulation of autophagy of mitochondrion. Each is linked with ZBTB17 in more than 14 cancer types. Because this analysis shows association rather than direction, both ZBTB17-to-partner and partner-to-ZBTB17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of translational initiation grouped by ZBTB17-low versus ZBTB17-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB17→partner) and Y-score (partner→ZBTB17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of translational initiation →	+0.069	+0.681	.001	.001	3	15
BONE	RISC complex assembly →	+0.134	+1.054	<.001	<.001	3	15
OESOPHAGUS	Regulation of autophagy of mitochondrion →	+0.116	+0.622	<.001	<.001	3	15
OESOPHAGUS	Retrograde transport, endosome to Golgi →	+0.074	+0.519	.001	.006	3	15
BONE	Negative regulation of mRNA splicing, via spliceosome →	+0.119	+1.022	<.001	<.001	3	14
BONE	Cellular response to methionine →	+0.105	+0.781	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,710 associations by consensus.

Regulation of translational initiation by ZBTB17 expression — BONE

Explore this box plot interactively →