ZBTB16

Across TCGA cell cohorts, ZBTB16 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZBTB16-associated genes across cancer lineages are LIPN, OR52E1, and POTEB3. Each is linked with ZBTB16 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZBTB16-to-partner and partner-to-ZBTB16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LIPN grouped by ZBTB16-low versus ZBTB16-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB16→partner) and Y-score (partner→ZBTB16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	LIPN →	+0.019	+4.977	<.001	.007	3	1
STOMACH	OR52E1 →	+0.023	+5.285	<.001	.003	3	1
OVARY	POTEB3 →	+0.040	+3.115	.002	.002	3	1
LARGE_INTESTINE	MLNR →	+0.089	+2.807	.006	.004	3	1
LARGE_INTESTINE	TBX18 →	+1.075	+3.215	.001	.009	3	1
LARGE_INTESTINE	SLC35G3 →	+0.005	+2.560	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

LIPN by ZBTB16 expression — SKIN

Explore this box plot interactively →