Across TCGA patient cohorts, ZBTB12 mutation is significantly associated with the total protein of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZBTB12-associated genes across cancer lineages are ACC1, IRS1, and p90 RSK. Each is linked with ZBTB12 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZBTB12-to-partner and partner-to-ZBTB12 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB12→partner) and Y-score (partner→ZBTB12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ACC1 →	+0.473	+3.000	.024	.037	3	1
UCEC	IRS1 →	-0.315	-3.000	.008	.037	3	1
UCEC	p90 RSK →	+0.306	+3.013	.005	.019	3	1
UCEC	Syk →	+0.430	+3.013	.047	.019	2	1
UCEC	JNK_pT183_Y185 →	-0.290	-2.986	.002	.037	1	1
UCEC	Annexin-1 →	+0.948	+3.000	.001	.037	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Exploration

ZBTB12 survival (RNA) · tumor vs normal (RNA) · all ZBTB12 data types