Across TCGA cell cohorts, ZBTB12 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZBTB12-associated genes across cancer lineages are HNRNPCL4, LRRC3C, and PHOX2B. Each is linked with ZBTB12 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZBTB12-to-partner and partner-to-ZBTB12 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB12→partner) and Y-score (partner→ZBTB12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	HNRNPCL4 →	+0.079	+3.793	<.001	.007	3	1
LARGE_INTESTINE	LRRC3C →	+0.352	+3.777	<.001	.007	3	1
BLOOD_Leukemia	PHOX2B →	+0.026	+4.365	<.001	.002	3	1
BLOOD_Leukemia	TCF21 →	+0.008	+3.705	.002	.007	3	1
BLOOD_Leukemia	NPFFR1 →	+0.015	+4.037	<.001	.004	3	1
BLOOD_Leukemia	TAS1R2 →	+0.015	+3.855	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

Exploration

ZBTB12 survival (RNA) · tumor vs normal (RNA) · all ZBTB12 data types