Across TCGA patient cohorts, ZBTB10 mutation is significantly associated with the RNA expression of many other genes, with 2,606 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZBTB10-associated genes across cancer lineages are MIR1183, POM121C, and CCL4. Each is linked with ZBTB10 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZBTB10-to-partner and partner-to-ZBTB10 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB10→partner) and Y-score (partner→ZBTB10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MIR1183 →	+0.336	+4.680	<.001	.007	3	3
UCEC	POM121C →	+0.392	+2.191	<.001	<.001	3	2
UCEC	CCL4 →	+0.772	+3.021	.001	<.001	3	2
UCEC	IKBKGP1 →	+0.065	+1.617	.002	.004	3	2
UCEC	RNA5SP411 →	+0.807	+1.628	<.001	.005	3	2
UCEC	TRBV12-4 →	+0.444	+2.150	.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,606 associations by consensus.

Exploration

ZBTB10 survival (RNA) · tumor vs normal (RNA) · all ZBTB10 data types