ZBTB10

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZBTB10 mutation is significantly associated with the total protein of many other genes, with 31 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZBTB10-associated genes across cancer lineages are PDCD4, PKC-delta_pS664, and PRDX1. Each is linked with ZBTB10 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZBTB10-to-partner and partner-to-ZBTB10 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB10→partner) and Y-score (partner→ZBTB10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECPDCD4 →-0.552-1.415.001.04632
UCECPKC-delta_pS664 →-0.119-2.000.008.02932
UCECPRDX1 →+0.244+2.584.001.01032
UCECAnnexin-1 →+0.617+2.604.001.00532
UCECShc_pY317 →-0.118-1.415.037.04632
UCECEGFR_pY1068 →-0.192-2.000.041.02931
Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

Exploration