Across TCGA cell cohorts, ZBTB10 mutation is significantly associated with the RNA expression of many other genes, with 33 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZBTB10-associated genes across cancer lineages are TMIGD1, H4C12, and CYP11B1. Each is linked with ZBTB10 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZBTB10-to-partner and partner-to-ZBTB10 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBTB10→partner) and Y-score (partner→ZBTB10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	TMIGD1 →	+0.023	+4.643	<.001	.008	3	2
CNS	H4C12 →	+0.943	+2.906	.001	.009	3	2
SOFT_TISSUE	CYP11B1 →	+0.013	+4.392	<.001	.004	3	1
OESOPHAGUS	SOX3 →	+0.059	+4.017	<.001	.007	3	1
PANCREAS	TMEM72 →	+0.048	+4.035	.003	.003	3	1
BLOOD_Myeloma	KRT35 →	+0.006	+4.807	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

Exploration

ZBTB10 survival (RNA) · tumor vs normal (RNA) · all ZBTB10 data types