ZBED9

Across TCGA patient cohorts, ZBED9 mutation is significantly associated with the RNA expression of many other genes, with 5,125 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZBED9-associated genes across cancer lineages are HJURP, CKAP2L, and HSPA9. Each is linked with ZBED9 in more than 5 cancer types. Because this analysis shows association rather than direction, both ZBED9-to-partner and partner-to-ZBED9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HJURP grouped by ZBED9-low versus ZBED9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBED9→partner) and Y-score (partner→ZBED9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	HJURP →	+0.479	+1.362	.001	.001	3	6
UCEC	CKAP2L →	+0.469	+1.778	.001	<.001	3	6
UCEC	HSPA9 →	+0.390	+1.970	<.001	<.001	3	5
UCEC	TOMM5 →	+0.387	+1.384	<.001	<.001	3	5
UCEC	UBE2T →	+0.499	+1.405	<.001	<.001	3	5
LUAD	BABAM1 →	+0.436	+3.620	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,125 associations by consensus.

HJURP by ZBED9 expression — UCEC

Explore this box plot interactively →