ZBED9

Across TCGA patient cohorts, ZBED9 mutation is significantly associated with the total protein of many other genes, with 49 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZBED9-associated genes across cancer lineages are C-Raf, TFRC, and ATM. Each is linked with ZBED9 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZBED9-to-partner and partner-to-ZBED9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C-Raf grouped by ZBED9-low versus ZBED9-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBED9→partner) and Y-score (partner→ZBED9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	C-Raf →	+0.204	+3.169	.038	.019	3	4
UCEC	TFRC →	+0.445	+1.678	.002	.019	3	4
BLCA	ATM →	-0.579	-3.169	.004	.018	3	3
UCEC	ASNS →	+0.382	+1.584	<.001	.004	3	3
COAD	Caspase-7-cleavedD198 →	+1.002	+3.178	.010	.010	3	3
UCEC	Caspase-8 →	-0.253	-1.874	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 49 associations by consensus.

C-Raf by ZBED9 expression — BLCA

Explore this box plot interactively →