ZBED8

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZBED8 mutation is significantly associated with the RNA expression of many other genes, with 2,592 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZBED8-associated genes across cancer lineages are PPP3R2, GTF2IP2, and RPL35AP3. Each is linked with ZBED8 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZBED8-to-partner and partner-to-ZBED8 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBED8→partner) and Y-score (partner→ZBED8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECPPP3R2 →+0.040+1.563<.001.00432
READGTF2IP2 →+0.099+5.257<.001.00232
READRPL35AP3 →+0.615+4.533<.001.00432
READLINC02621 →+0.554+4.724<.001.00332
LUSCRNA5SP176 →+0.351+7.924<.001.00832
SKCMRSL24D1P2 →+0.165+4.531<.001.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,592 associations by consensus.

Exploration