Across TCGA cell cohorts, ZBED8 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,691 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ZBED8-associated GO terms across cancer lineages are Alternative mRNA splicing, via spliceosome, Regulation of syncytium formation by plasma membrane fusion, and Negative regulation of myoblast fusion. Each is linked with ZBED8 in more than 15 cancer types. Because this analysis shows association rather than direction, both ZBED8-to-partner and partner-to-ZBED8 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBED8→partner) and Y-score (partner→ZBED8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Alternative mRNA splicing, via spliceosome →	+0.136	+0.923	<.001	<.001	3	16
OESOPHAGUS	Regulation of syncytium formation by plasma membrane fusion →	+0.176	+1.065	<.001	.003	3	15
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.145	+0.979	.001	<.001	3	14
OESOPHAGUS	Spliceosomal complex assembly →	+0.138	+1.128	.004	.002	3	14
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.144	+0.964	.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Nucleotide-excision repair →	+0.075	+0.693	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,691 associations by consensus.

Exploration

ZBED8 survival (RNA) · tumor vs normal (RNA) · all ZBED8 data types