ZBED6

Across TCGA cell cohorts, ZBED6 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,343 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZBED6-associated GO terms across cancer lineages are Viral translational termination-reinitiation, Cilium or flagellum-dependent cell motility, and Negative regulation of syncytium formation by plasma membrane fusion. Each is linked with ZBED6 in more than 15 cancer types. Because this analysis shows association rather than direction, both ZBED6-to-partner and partner-to-ZBED6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Viral translational termination-reinitiation grouped by ZBED6-low versus ZBED6-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBED6→partner) and Y-score (partner→ZBED6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Viral translational termination-reinitiation →	+0.101	+1.493	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Cilium or flagellum-dependent cell motility →	-0.104	-1.002	<.001	<.001	3	15
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.142	+1.172	.002	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Retrograde transport, endosome to Golgi →	+0.088	+1.508	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Cilium-dependent cell motility →	-0.104	-1.002	<.001	<.001	3	15
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.146	+1.177	.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,343 associations by consensus.

Viral translational termination-reinitiation by ZBED6 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →