ZBED5-AS1

Across TCGA pan-cancer cohorts, ZBED5-AS1 RNA is linked to patient survival in 28 of 34 cancer types, making it the most broadly survival-associated ZBED5-AS1 data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher ZBED5-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated ZBED5-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and KIRP show a favorable association.

UCEC, KIRP, and CHOL are the cancer types where ZBED5-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Tertile	All	0.754	0.598	.002	52	view →
KIRP	OS	Quartile	All	0.914	0.760	.004	47	view →
CHOL	DFS	Median	II,III,IV	0.621	0.142	.001	40	view →
KIRC	DFS	Tertile	All	0.743	0.496	<.001	40	view →
MESO	OS	Quartile	All	0.616	0.320	.002	34	view →
LAML	DFS	Quartile	All	0.424	0.683	.004	32	view →
UVM	DFS	Median	All	0.718	0.431	.003	30	view →
OV	OS	Quartile	III,IV	0.723	0.577	.013	30	view →
THCA	DFS	Median	All	0.890	0.774	.001	27	view →
HNSC	DFS	Tertile	III,IV	0.587	0.717	.002	26	view →
STAD	OS	Tertile	III,IV	0.233	0.723	.005	24	view →
PRAD	DFS	Median	All	0.879	0.687	<.001	20	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 28 lineages.

ZBED5-AS1–UCEC (DFS)

Open the UCEC breakdown →