ZBED3

Across TCGA cell cohorts, ZBED3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,948 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZBED3-associated GO terms across cancer lineages are Zymogen activation, Regulation of body fluid levels, and Subtelomeric heterochromatin formation. Each is linked with ZBED3 in more than 10 cancer types. Because this analysis shows association rather than direction, both ZBED3-to-partner and partner-to-ZBED3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Zymogen activation grouped by ZBED3-low versus ZBED3-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBED3→partner) and Y-score (partner→ZBED3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Zymogen activation →	-0.184	-0.744	<.001	.003	3	10
PANCREAS	Regulation of body fluid levels →	-0.071	-0.789	.002	.001	2	11
URINARY_TRACT	Subtelomeric heterochromatin formation →	+0.095	+1.004	<.001	<.001	3	9
BONE	Cell-substrate adhesion →	-0.154	-0.671	.002	.009	2	10
LARGE_INTESTINE	Acrosomal vesicle exocytosis →	+0.988	+0.970	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Negative regulation of hemostasis →	-0.155	-0.858	.002	.002	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,948 associations by consensus.

Zymogen activation by ZBED3 expression — PANCREAS

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