ZBED3-AS1

Across TCGA pan-cancer cohorts, ZBED3-AS1 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of ZBED3-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where ZBED3-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types ZBED3-AS1 is over-expressed in tumor, although a few such as THCA and BRCA show the opposite, repressed pattern.

THCA, COAD, and BRCA are the cancer types where ZBED3-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ZBED3-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Male	All	−0.621	<.001	10	view →
COAD	All	II,III,IV	+0.167	<.001	9	view →
BRCA	All	All	−0.581	<.001	6	view →
LUSC	Male	II,III,IV	−0.405	<.001	6	view →
KIRC	Male	All	−0.263	<.001	6	view →
LIHC	All	All	+0.187	<.001	5	view →
KICH	All	All	−0.426	<.001	4	view →
LUAD	Female	II,III,IV	−0.330	<.001	4	view →
CHOL	All	All	+0.271	.021	3	view →
ESCA	All	All	−0.444	.039	1	view →
HNSC	Male	III,IV	+0.126	.025	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

ZBED3-AS1–THCA

Open the THCA breakdown →