ZBED2

Across TCGA cell cohorts, ZBED2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,761 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZBED2-associated GO terms across cancer lineages are Cell-substrate junction organization, Integrin-mediated signaling pathway, and Regulation of ruffle assembly. Each is linked with ZBED2 in more than 10 cancer types. Because this analysis shows association rather than direction, both ZBED2-to-partner and partner-to-ZBED2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cell-substrate junction organization grouped by ZBED2-low versus ZBED2-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBED2→partner) and Y-score (partner→ZBED2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Cell-substrate junction organization →	+0.189	+2.327	<.001	<.001	3	11
BREAST	Integrin-mediated signaling pathway →	+0.138	+1.030	.002	.006	3	11
OVARY	Regulation of ruffle assembly →	+0.131	+2.864	<.001	<.001	3	10
LARGE_INTESTINE	Positive regulation of ATP biosynthetic process →	+0.134	+2.997	<.001	<.001	3	10
BREAST	Intermediate filament-based process →	+0.191	+1.306	<.001	.009	3	10
OESOPHAGUS	Cell-substrate junction assembly →	+0.201	+2.377	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,761 associations by consensus.

Cell-substrate junction organization by ZBED2 expression — OESOPHAGUS

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