ZBED2

Across TCGA cell cohorts, ZBED2 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible ZBED2-associated genes across cancer lineages are OR4D6, OR10G3, and PRAMEF10. Each is linked with ZBED2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZBED2-to-partner and partner-to-ZBED2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR4D6 grouped by ZBED2-low versus ZBED2-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBED2→partner) and Y-score (partner→ZBED2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	OR4D6 →	+0.016	+5.807	<.001	.001	3	1
SKIN	OR10G3 →	+0.006	+6.022	<.001	.001	3	1
LUNG_SCLC	PRAMEF10 →	+0.885	+4.643	<.001	.004	3	1
LUNG_SCLC	PRAMEF20 →	+0.367	+4.269	<.001	.005	3	1
LUNG_SCLC	PRAMEF17 →	+0.010	+4.643	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

OR4D6 by ZBED2 expression — OVARY

Explore this box plot interactively →