Across TCGA patient cohorts, ZBED1 mutation is significantly associated with the total protein of many other genes, with 42 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZBED1-associated genes across cancer lineages are Stathmin, YAP_pS127, and CD31. Each is linked with ZBED1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZBED1-to-partner and partner-to-ZBED1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZBED1→partner) and Y-score (partner→ZBED1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Stathmin →	+0.209	+3.178	.005	.010	3	3
STAD	YAP_pS127 →	-0.488	-3.169	.002	.019	3	2
STAD	CD31 →	-0.222	-3.169	.003	.019	3	2
SKCM	Caspase-8 →	-0.198	-3.459	.006	.005	3	2
UCEC	JNK2 →	+0.150	+1.594	.010	.010	3	2
UCEC	MSH6 →	-0.359	-2.000	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 42 associations by consensus.

Exploration

ZBED1 survival (RNA) · tumor vs normal (RNA) · all ZBED1 data types