Across TCGA cell cohorts, ZAR1L mutation is significantly associated with the mutation status of many other genes, with 351 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ZAR1L-associated genes across cancer lineages are LRRD1, RCBTB2, and HERC3. Each is linked with ZAR1L in more than 1 cancer types. Because this analysis shows association rather than direction, both ZAR1L-to-partner and partner-to-ZAR1L results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZAR1L→partner) and Y-score (partner→ZAR1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	LRRD1 →	+5.824	+5.824	.002	.002	1	2
SKIN	RCBTB2 →	+5.824	+5.824	.002	.002	1	2
SKIN	HERC3 →	+4.824	+5.392	.004	.004	1	2
SKIN	ZNF787 →	+4.239	+5.053	.007	.007	1	2
SKIN	OR8K1 →	+4.239	+5.053	.007	.007	1	2
SKIN	FAM160B1 →	+4.824	+5.392	.004	.004	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 351 associations by consensus.

Exploration

ZAR1L survival (RNA) · tumor vs normal (RNA) · all ZAR1L data types