ZADH2

Across TCGA patient cohorts, ZADH2 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,624 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZADH2-associated proteins across cancer lineages are SMAD4, CXXC1, and KIAA1143. Each is linked with ZADH2 in more than 8 cancer types. Because this analysis shows association rather than direction, both ZADH2-to-partner and partner-to-ZADH2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZADH2 versus SMAD4 in COAD, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZADH2→partner) and Y-score (partner→ZADH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	SMAD4 →	+0.298	+0.575	.001	<.001	3	9
GBM	CXXC1 →	+0.246	+0.463	<.001	<.001	3	6
GBM	KIAA1143 →	+0.321	+0.418	<.001	<.001	3	6
LSCC	WDR5 →	+0.272	+0.456	<.001	<.001	3	6
COAD	VPS4B →	+0.290	+0.530	<.001	<.001	3	6
BRCA	ZNF24 →	+0.450	+0.748	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,624 associations by consensus.

ZADH2 vs SMAD4 — COAD

Explore this scatter interactively →