Across TCGA patient cohorts, ZACN RNA expression is significantly associated with the protein abundance of many other proteins, with 11,419 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZACN-associated proteins across cancer lineages are SUGP1, HNRNPH1, and ARHGEF1_S631. Each is linked with ZACN in more than 4 cancer types. Because this analysis shows association rather than direction, both ZACN-to-partner and partner-to-ZACN results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZACN→partner) and Y-score (partner→ZACN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SUGP1 →	+0.205	+0.314	<.001	<.001	3	5
GBM	HNRNPH1 →	+0.197	+0.319	<.001	<.001	3	5
CCRCC	ARHGEF1_S631 →	-0.657	-0.241	.001	<.001	3	5
LSCC	DDX42 →	+0.244	+0.352	<.001	<.001	3	5
LSCC	DHX8 →	+0.281	+0.281	<.001	<.001	3	5
LSCC	EIF4A3 →	+0.274	+0.300	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,419 associations by consensus.

Exploration

ZACN survival (RNA) · tumor vs normal (RNA) · all ZACN data types