ZACN

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ZACN RNA expression is significantly associated with the go_rna of many other GO terms, with 3,580 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZACN-associated GO terms across cancer lineages are Negative regulation of DNA-templated transcription, elongation, Vacuole organization, and Regulation of RNA splicing. Each is linked with ZACN in more than 14 cancer types. Because this analysis shows association rather than direction, both ZACN-to-partner and partner-to-ZACN results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZACN→partner) and Y-score (partner→ZACN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STOMACHNegative regulation of DNA-templated transcription, elongation →+0.108+0.969.002<.001315
BLOOD_MyelomaVacuole organization →+0.056+1.014<.001<.001315
UPPER_AERODIGESTIVE_TRACTRegulation of RNA splicing →+0.080+1.015<.001<.001313
LUNG_SCLCLate endosome to lysosome transport →+0.142+1.043<.001<.001313
LUNG_SCLCSpliceosome conformational change to release U4 (or U4atac) and U1 (or U11) →+0.091+0.921<.001<.001312
LARGE_INTESTINEPositive regulation of intracellular steroid hormone receptor signaling pathway →+0.168+0.608<.001<.001312
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,580 associations by consensus.

Exploration