YY1P1

Across TCGA pan-cancer cohorts, YY1P1 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated YY1P1 data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher YY1P1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated YY1P1 expression acts as an unfavorable survival marker, although some lineages such as ESCA and SKCM show a favorable association.

UCS, TGCT, and ESCA are the cancer types where YY1P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	DFS	Tertile	IV	0.230	0.767	.009	36	view →
TGCT	DFS	Tertile	II,III,IV	0.674	1.000	.007	36	view →
ESCA	OS	Tertile	III,IV	0.600	0.280	.014	30	view →
HNSC	OS	Tertile	III,IV	0.399	0.717	.002	27	view →
KIRC	DFS	Quartile	IV	0.325	0.595	.003	27	view →
LUSC	DFS	Tertile	III,IV	0.104	0.744	<.001	26	view →
COAD	DFS	Median	III,IV	0.477	0.695	.010	25	view →
SKCM	OS	Tertile	II,III,IV	0.641	0.345	.011	24	view →
OV	OS	Quartile	IV	0.568	0.800	.019	12	view →
KIRP	DFS	Tertile	All	0.842	0.942	.004	12	view →
THCA	DFS	Tertile	IV	0.654	0.962	.017	9	view →
READ	DFS	Tertile	IV	0.179	0.671	<.001	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

YY1P1–UCS (DFS)

Open the UCS breakdown →