YWHAQ

Across TCGA patient cohorts, YWHAQ protein abundance is significantly associated with the RNA expression of many other genes, with 15,656 significant associations in total. GBM shows the largest number of these associations.

The most reproducible YWHAQ-associated genes across cancer lineages are KIF3C, NOL10, and DTD1. Each is linked with YWHAQ in more than 6 cancer types. Because this analysis shows association rather than direction, both YWHAQ-to-partner and partner-to-YWHAQ results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, YWHAQ versus KIF3C in GBM, with a Pearson correlation of 0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (YWHAQ→partner) and Y-score (partner→YWHAQ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	KIF3C →	+0.773	+0.401	<.001	<.001	3	7
LSCC	NOL10 →	+0.511	+0.285	<.001	<.001	3	6
LSCC	DTD1 →	+0.608	+0.373	<.001	<.001	3	6
OV	ACP1 →	+0.508	+0.268	<.001	<.001	3	6
OV	FAM220A →	+0.447	+0.256	.001	.001	3	6
OV	GPN1 →	+0.558	+0.288	<.001	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,656 associations by consensus.

YWHAQ vs KIF3C — GBM

Explore this scatter interactively →