YWHAQ

Across TCGA cell cohorts, YWHAQ protein abundance is significantly associated with the RNA expression of many other genes, with 7,260 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible YWHAQ-associated genes across cancer lineages are PSMC3IP, SAP30, and ACD. Each is linked with YWHAQ in more than 6 cancer types. Because this analysis shows association rather than direction, both YWHAQ-to-partner and partner-to-YWHAQ results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, YWHAQ versus PSMC3IP in URINARY_TRACT, with a Pearson correlation of -0.71.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (YWHAQ→partner) and Y-score (partner→YWHAQ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	PSMC3IP →	-1.295	-0.777	.005	<.001	3	6
STOMACH	SAP30 →	-0.973	-0.631	.005	<.001	3	6
OVARY	ACD →	-0.810	-0.384	.001	.003	3	6
BLOOD_Leukemia	DCLRE1B →	-0.678	-0.735	<.001	<.001	3	6
BLOOD_Leukemia	DSN1 →	-0.745	-0.737	.001	.002	2	7
BLOOD_Leukemia	HMGB2 →	-0.876	-0.916	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,260 associations by consensus.

YWHAQ vs PSMC3IP — URINARY_TRACT

Explore this scatter interactively →